Alessandra Fiorio Pla
Professore/Professoressa ordinario/a
- Dipartimento di Scienze della Vita e Biologia dei Sistemi
- SSD: BIO/09 - fisiologia
- ORCID: orcid.org/0000-0003-4576-1594
Contatti
- 0116704660
- alessandra.fiorio@unito.it
- Via Accademia Albertina13 - 10123 Torino
- https://www.dbios.unito.it/persone/alessandra.fioriopla
- VCard contatti
Presso
- Department of Life Sciences and Systems Biology
- Dipartimento di Scienze della Vita e Biologia dei Sistemi
- Cellular and Molecular Biology
- Corso di laurea in Scienze Biologiche (L-13)
- Corso di laurea magistrale in Biotecnologie Industriali
- Corso di laurea magistrale in Fisica
- Dottorato in Sistemi Complessi per le Scienze della Vita (fino al ciclo 35) - PhD Programme in Complex Systems for Life Sciences (until 35th cycle)
- PhD in Complex Systems for Quantitative Biomedicine
- PhD Programme in Complex Systems for Life Sciences (until 35th cycle)
Curriculum vitae
Prodotti della ricerca
Tutti i miei prodotti della ricercaProdotti della ricerca selezionati
Selected pubblications (2013-2023):
- Folcher, A; Gordienko, D; Iamshanova, O; Bokhobza, A; Shapovalov, G; Kannancheri-Puthooru, D; Mariot, P; Allart, L; Desruelles, E; Spriet, C; Diez, R; Oullier, T; Marionneau-Lambot, S; Brisson, L; Geraci, S; Impheng, H; Lehen'kyi, V; Haustrate, A; Mihalache, A; Gosset, P; Chadet, S; Retif, S; Laube, M; Sobilo, J; Lerondel, S; Villari, G; Serini, G; Fiorio Pla, A; Roger, S; Fromont-Hankard, G; Djamgoz, M; Clezardin, P; Monteil, A; Prevarskaya, N. NALCN-mediated sodium influx confers metastatic prostate cancer cell invasiveness (2023) EMBO J. doi: 15252/embj.2022112198
- Audero, MM; Carvalho, TMA;Ruffinatti, FA; Loeck, T; Yassine, M; Chinigò, G; Folcher, A; Farfariello, V; Amadori, S; Vaghi, C; Schwab, A; Reshkin, SJ; Cardone, RA; Prevarskaya, N; Fiorio Pla, A. Acidic Growth Conditions Promote Epithelial-to-Mesenchymal Transition to Select More Aggressive PDAC Cell Phenotypes In Vitro (2023). Cancers Volume 15, Issue 9 May 2023 Article number 2572
- Pontremoli C.; Chinigo' G.; Galliano S.; Moran Plata M.J.; Dereje D.M.; Sansone E.; Gilardino A.; Barolo C.; Fiorio Pla A.; Visentin S.; Barbero N. Photosensitizers for photodynamic therapy: Structure-activity analysis of cyanine dyes through design of experiments (2023). DYES AND PIGMENTS doi: 10.1016/j.dyepig.2022.111047
- Audero, MM; Prevarskaya, N; Fiorio Pla, A. Ca2+ Signalling and Hypoxia/Acidic Tumour Microenvironment Interplay in Tumour Progression (2022). Int J Mol Med. Doi: 10.3390/ijms23137377
- Chinigò G, Gonzalez-Paredes A., Gilardino A., Barbero N., Barolo C., Gasco P., Fiorio Pla A.*, Visentin S. Polymethine dyes-loaded solid lipid nanoparticles (SLN) as promising photosensitizers for biomedical applications (2022). Spectrochim Acta A Mol Biomol Spectrosc Apr 15;271:120909. doi: 10.1016/j.saa.2022.120909. Epub 2022 Jan 19.
- Villari G, Enrico Bena C, Del Giudice M, Gioelli N, Sandri C, Camillo C, Fiorio Pla A, Bosia C, Serini G. (2020). Distinct retrograde microtubule motor sets drive early and late endosome transport. EMBO J. Nov 20;39(24):e103661. doi: 10.15252/embj.2019103661.
- Chinigò G.; Fiorio Pla A.; Gkika D. (2020). TRP Channels and Small GTPases Interplay in the Main Hallmarks of Metastatic Cancer. Front Pharmacol Sep 29;11:581455. doi:10.3389/fphar.2020.581455. eCollection 2020.
- Scarpellino G, Munaron L, Cantelmo AR, Fiorio Pla A. Calcium-Permeable Channels in Tumor Vascularization: Peculiar Sensors of Microenvironmental Chemical and Physical Cues. Rev Physiol Biochem Pharmacol (2020); DOI: 10.1007/112_2020_32
- Bernardini M, Brossa A, Chinigo G, Grolez GP…Fiorio Pla A*, Gkika D*: Transient Receptor Potential Channel Expression Signatures in Tumor-Derived Endothelial Cells: Functional Roles in Prostate Cancer Angiogenesis. Cancers(Basel) 2019;11:956.
- Luganini A., Di Nardo G, Munaron L., Gilardi G., Fiorio Pla A and Gribaudo G.: Human cytomegalovirus US21 protein is a viroporin that modulates calcium homeostasis and protects cells against apoptosis. PNAS (2018) 115 (52) E12370-E12377
- Genova T, Grolez GP, Camillo C, Bernardini M, Bokhobza A, Richard E, Scianna M, Lemonnier L, Valdembri D, Munaron L, Philips MR, Mattot V, Serini G, Prevarskaya N, Gkika D, Fiorio Pla A (2017). TRPM8 inhibits endothelial cell migration via a non-channel function by trapping the small GTPase Rap1. J Cell Biol. May 26. pii: jcb.201506024. doi: 10.1083/jcb.201506024.
- Iamshanova O, Fiorio Pla A, Prevarskaya N. (2017) Molecular mechanisms of tumor invasion: regulation by calcium signals. J Physiol. Mar 17. doi: 10.1113/JP272844.
- Fiorio Pla A, Kondratska K, Prevarskaya N. (2016). STIM and ORAI proteins: crucial roles in hallmarks of cancer. Am J Physiol Cell Physiol. Apr 1;310(7):C509-19. doi: 10.1152/ajpcell.00364.2015M.
- Patella F, Schug ZT, Persi E, Neilson LJ, Erami Z, Avanzato D, Maione F, Hernandez-Fernaud JR, Mackay G, Zheng L, Reid S, Frezza C, Giraudo E, Fiorio Pla A, Anderson K, Ruppin E, Gottlieb E, Zanivan S. (2015) Proteomics-based metabolic modelling reveals that fatty acid oxidation controls endothelial cell permeability. Mol Cell Proteomics. 2015 Jan 8. pii: mcp.M114.045575.
- Gkika D, Lemonnier L, Shapovalov G, Gordienko D, Poux C, Bernardini M, Bokhobza A, Bidaux G, Degerny C, Verreman K, Guarmit B, Benahmed M, de Launoit Y, Bindels RJ, Fiorio Pla A, Prevarskaya N (2015). TRP channel-associated factors are a novel protein family that regulates TRPM8 trafficking and activity. J Cell Biol. Jan 5;208(1):89-107. doi: 10.1083/jcb.201402076.
- Fiorio Pla A, Munaron L. (2014). Functional properties of ion channels and transporters in tumour vascularization Philos Trans R Soc Lond B Biol Sci.
Insegnamenti
- Biofisica cellulare e molecolare - DM 270 (MFN0250)
Corso di laurea magistrale in Biotecnologie Industriali - Biophysics (FIS0197)
Corso di laurea magistrale in Fisica - Cell Biology and Physiopatholology
PhD Programme in Complex Systems for Life Sciences (until 35th cycle) - Cell Biology and Physiopatholology
Dottorato in Sistemi Complessi per le Scienze della Vita (fino al ciclo 35) - PhD Programme in Complex Systems for Life Sciences (until 35th cycle) - FISIOLOGIA GENERALE (corso A) (MFN0408)
Corso di laurea in Scienze Biologiche (L-13) - FISIOLOGIA GENERALE (corso B) (MFN0408)
Corso di laurea in Scienze Biologiche (L-13) - Introduction to Cell Physiology
PhD Programme in Complex Systems for Life Sciences (until 35th cycle) - Introduction to Cell Physiology
Dottorato in Sistemi Complessi per le Scienze della Vita (fino al ciclo 35) - PhD Programme in Complex Systems for Life Sciences (until 35th cycle) - Introduction to Cell Physiology
PhD in Complex Systems for Quantitative Biomedicine - NEUROPHYSIOLOGY (SVB0102)
Cellular and Molecular Biology
Biofisica (MFN1460)
LM in Biotecnologie Industriali
Temi di ricerca
Per maggiori dettagli è possibile consultareil sito ORCID https://orcid.org/0000-0003-4576-1594
For scientific production see Web of Science ResearcherID
B-6646-2012
or ORCID page: https://orcid.org/0000-0003-4576-1594
For on going project please visit my ORCID page: https://orcid.org/0000-0003-4576-1594
Tutti i miei progetti di ricerca
Attività in agenda
Organi
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per ricevimento si prega di prendere contatti via e-mail o per telefonoFaculty